Who Controls Mifepristone? The Politics Blocking a New Era of Contraception

Mifepristone “works against endometriosis. It works against myoma [fibroids]. We are now involved in a study group that looks at whether it can prevent breast cancer,” says pioneering reproductive-health advocate Dr. Rebecca Gomperts. “It has so many potential uses, and it hasn’t been [developed].

“If we as women don’t make sure that it becomes available to meet our needs … then it won’t happen.”

This is the final installment of a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

Mifepristone Could Treat Endometriosis, Some Cancers, Depression and Chronic Illness—If Politics Didn’t Interfere

Across a range of conditions that disproportionately affect women, research into mifepristone’s potential has been slowed, defunded or blocked altogether. Nowhere is that clearer than in the treatment of endometriosis and other serious illnesses that leave millions of women in chronic pain.

Endometriosis—when endometrium cells grow outside the uterus—afflicts an estimated 10 percent of reproductive-age women. It can lead to chronic pelvic and back pain, heavy or abnormal bleeding, pain during sex or bowel movements, fatigue, bloating, digestive issues, infertility, anxiety and depression.

Mifepristone can help—it blocks the progesterone causing the cellular growth and decreases the size of existing endometrial lesions, thereby relieving painful symptoms. But antiabortion politics have obstructed the development of the medication for these uses in the U.S.

Researchers have also produced studies showing mifepristone is effective for treating ovarian and breast cancer, chronic inflammatory diseases, and several psychiatric disorders, including major depressive disorder, post-traumatic stress disorder (PTSD) and psychotic depression.

This is Part 2 of 3 in a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

‘The Moral Property of Women’: Mifepristone, Fibroids and the Stakes of Suppressed Science

Despite mifepristone’s broad medical promise, its development has been repeatedly stymied by abortion opponents who fear wider availability would weaken their attempts to suppress abortion access.

More than 26 million women in the U.S. are affected by fibroids, which are noncancerous growths of the uterus that can reach the size of a grapefruit or larger. Treatment too often defaults to invasive surgery, either removing the fibroids or performing hysterectomies.

In China today, a three-month regimen of 10 milligrams of mifepristone per day is the approved protocol for treating fibroids. Meanwhile, American women still do not have access to this very effective nonsurgical treatment.

This is Part 1 of 3 in a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.