Who Controls Mifepristone? The Politics Blocking a New Era of Contraception

Mifepristone “works against endometriosis. It works against myoma [fibroids]. We are now involved in a study group that looks at whether it can prevent breast cancer,” says pioneering reproductive-health advocate Dr. Rebecca Gomperts. “It has so many potential uses, and it hasn’t been [developed].

“If we as women don’t make sure that it becomes available to meet our needs … then it won’t happen.”

This is the final installment of a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

Mifepristone Could Treat Endometriosis, Some Cancers, Depression and Chronic Illness—If Politics Didn’t Interfere

Across a range of conditions that disproportionately affect women, research into mifepristone’s potential has been slowed, defunded or blocked altogether. Nowhere is that clearer than in the treatment of endometriosis and other serious illnesses that leave millions of women in chronic pain.

Endometriosis—when endometrium cells grow outside the uterus—afflicts an estimated 10 percent of reproductive-age women. It can lead to chronic pelvic and back pain, heavy or abnormal bleeding, pain during sex or bowel movements, fatigue, bloating, digestive issues, infertility, anxiety and depression.

Mifepristone can help—it blocks the progesterone causing the cellular growth and decreases the size of existing endometrial lesions, thereby relieving painful symptoms. But antiabortion politics have obstructed the development of the medication for these uses in the U.S.

Researchers have also produced studies showing mifepristone is effective for treating ovarian and breast cancer, chronic inflammatory diseases, and several psychiatric disorders, including major depressive disorder, post-traumatic stress disorder (PTSD) and psychotic depression.

This is Part 2 of 3 in a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

‘The Moral Property of Women’: Mifepristone, Fibroids and the Stakes of Suppressed Science

Despite mifepristone’s broad medical promise, its development has been repeatedly stymied by abortion opponents who fear wider availability would weaken their attempts to suppress abortion access.

More than 26 million women in the U.S. are affected by fibroids, which are noncancerous growths of the uterus that can reach the size of a grapefruit or larger. Treatment too often defaults to invasive surgery, either removing the fibroids or performing hysterectomies.

In China today, a three-month regimen of 10 milligrams per day is the approved protocol for treating fibroids. Meanwhile, American women still do not have access to this very effective nonsurgical treatment.

This is Part 1 of 3 in a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

Abortion Continues to Increase in 2025 as Telehealth Expands, Especially in States with Bans and Restrictions

Despite many states imposing sweeping abortion bans after Dobbs, more Americans are having abortions, not fewer, according to the Society of Family Planning’s latest #WeCount report.

“Abortion bans don’t stop people from needing and pursuing essential abortion care,” said Alison Norris, M.D., Ph.D., professor at The Ohio State University’s College of Public Health and #WeCount co-chair.

Despite these increases, Ushma Upadhyay, professor and fellow #WeCount co-chair, warned that unwarranted attacks on telehealth abortion may restrict access in the future. “This care is under assault by abortion opponents’ relentless attacks on mifepristone and telehealth—even though medication abortion is backed by a 25-year track record of safety and gold-standard science, and research shows that telehealth abortion is just as safe and effective as in-person care.”  

A Global Telehealth First: Women Help Women Begins Producing Abortion Pill Combipack

The feminist telehealth provider Women Help Women is redesigning how abortion pills are packaged to reflect what users actually need: a combination pack that includes one mifepristone tablet and eight misoprostol tablets for use up to 12 weeks of pregnancy.

“It’s a huge revolution of who actually gets to decide when, how and with the support of whom they can have an abortion and until when,” said Women Help Women coexecutive director Kinga Jelinska. “It centers the needs of users rather than institutions or markets. The underlying notion is that abortion can be friendly, and abortion can be easy.” 

Self-managed abortion is disruptive. We were told that abortion is a difficult decision; that it has to be difficult to access, and that only doctors control it. Self-managed abortion subverts that,” said Lucía Berro Pizzarossa, fellow coexecutive founder.

International Telehealth Provider ‘Abortion Pills in Private’ Ready to Ramp Up if FDA Restricts Mifepristone

As Trump’s FDA threatens to block U.S.-based medical providers from offering telehealth abortion, one international telehealth provider—Abortion Pills in Private—has vowed to continue providing mifepristone and misoprostol to U.S.-based patients, no matter what.

Their commitment is clear: “We will continue to send mifepristone, even if the FDA takes it off the market inside the U.S.. … We want to make this service easy, the best experience that it can be, with dignity. You can just go online, and it’s easy, and there’s no judgment. If you need this, we are here for you. Here are your pills. Here’s the support service that you need. You can do this from home. Whatever the reason is, we want to have that service there for you to be able to do that, no matter where you live.”

Their service and determination grew directly out of the post-Roe crisis. People find Abortion Pills in Private through the Plan C website. Since March 2024, they have served almost 3,500 patients in the U.S., most of them living in the hardest-hit states—those with abortion bans and severe restrictions. “They are from all over, but they are very much from banned states. Texas is always number one. Then Florida, Georgia. Even Ohio and Pennsylvania. There are some blue states too.”

Shout Your Abortion Short Films Seek to Normalize Keeping Abortion Pills at Home: ‘You Always Have Options’

The grassroots abortion-stigma-busting juggernaut Shout Your Abortion has released two new powerful public service announcements urging people across the U.S. to order abortion pills in advance to have on hand, in case they have an unwanted pregnancy.

Made by Detroit-based filmmaker Na Forest Lim, the short films follow two women—a teenager named Dani and a single mother in her 30s named Poppy—who find out they are pregnant and use abortion pills at home, supported by friends and family.

Both of the main characters have easy access to abortion pills: Dani’s friend arrives with pills in her backpack, and Poppy keeps a pack tucked away in her top dresser drawer.

Building on that vision of easy access, the Dani PSA shows what it looks like when abortion pills are already part of teenagers’ lives and a pregnancy never has the chance to become a crisis.

Inside the Global Network of Abortion Doulas Supporting Self-Managed Care

As barriers to clinic-based abortion care have increased in recent years, an increasing number of women are self-managing their abortions: finding and using abortion pills independently of the formal medical system. They are obtaining abortion pills through online abortion pill services, community networks sharing pills for free and websites selling pills.

To support self-managed abortion, feminists are creating a global network of online abortion doulas—trained companions who offer one-on-one support by phone, email and text to people using abortion pills. A leader in this effort is the organization Rouge Doulas, which runs the Rouge Abortion Doula School.

International Telehealth Provider ‘Women on Web’ Vows to Keep Abortion Pills Flowing to the U.S., No Matter What

As Republicans push the FDA to restrict mifepristone, the international online abortion service Women on Web is reassuring Americans that they will continue to support access to abortion pills in all 50 states, no matter what. Women on Web has served over 130,000 people worldwide since 2005 and began serving the U.S. in July 2024.

Venny Ala-Siurua, executive director of Women on Web, was recently named to the Top 100 Canada’s Most Powerful Women by the Women’s Executive Network Academe. Ms. spoke with Ala-Siurua about how their service connects people with pills, how they’re removing medical gatekeeping, and how they’re defending abortion access against digital censorship.

“We’ve always focused on countries where there are high restrictions on abortion. Unfortunately, the situation in some of the states in the U.S. qualifies now. … Many pharmacies and providers have stepped up internationally to support the U.S. and found ways of dispensing and shipping medicines really, really fast. …

“We are receiving around 30 requests per day from people in the U.S., though that number can rise during major political moments—for example, when Trump was elected or took office. Our U.S. care seekers live primarily in states with abortion bans. Globally, we currently handle approximately 4,000 requests each month.”

Repro Groups Sue Michigan Over Law Denying Pregnant Women Control of Their Bodies in End-of-Life Decisions

Bodily autonomy shouldn’t vanish with a positive pregnancy test—yet in Michigan, it can.

On Oct. 23, a coalition of Michigan women, physicians and patient advocates filed a lawsuit, Koskenojo v. Whitner, challenging the constitutionality of Michigan’s pregnancy-exclusion law that forces life support on pregnant women by denying incapacitated pregnant patients the right to refuse life-sustaining treatment. The case relies on a voter-approved 2022 constitutional amendment that explicitly protects “the right to make and effectuate decisions about all matters relating to pregnancy.”

One plaintiff—Nikki Sapiro Vinckier of Birmingham, Mich.—explained her objections to Michigan’s pregnancy exclusion law. “As a woman and a mother, it’s infuriating to know that my body can still be regulated more than it’s respected. As a trained OB-GYN physician assistant, I know this law protects no one—it only punishes those who can get pregnant. The pregnancy exclusion clause isn’t about safety or care. It’s about control. There is no place for a law that discriminates against pregnant people in a state that claims to trust women.”