Chronic Fatigue and Illness

Mifepristone Could Treat Endometriosis, Some Cancers, Depression and Chronic Illness—If Politics Didn’t Interfere

PUBLISHED 1/21/2026 by

Across a range of conditions that disproportionately affect women, research into mifepristone’s potential has been slowed, defunded or blocked altogether. Nowhere is that clearer than in the treatment of endometriosis and other serious illnesses that leave millions of women in chronic pain.

Endometriosis—when endometrium cells grow outside the uterus—afflicts an estimated 10 percent of reproductive-age women. It can lead to chronic pelvic and back pain, heavy or abnormal bleeding, pain during sex or bowel movements, fatigue, bloating, digestive issues, infertility, anxiety and depression.

Mifepristone can help—it blocks the progesterone causing the cellular growth and decreases the size of existing endometrial lesions, thereby relieving painful symptoms. But antiabortion politics have obstructed the development of the medication for these uses in the U.S.

Researchers have also produced studies showing mifepristone is effective for treating ovarian and breast cancer, chronic inflammatory diseases, and several psychiatric disorders, including major depressive disorder, post-traumatic stress disorder (PTSD) and psychotic depression.

This is Part 2 of 3 in a new series, “The Moral Property of Women: How Antiabortion Politics Are Withholding Medical Care,” a serialized version of the Winter 2026 print feature article.

Sneak Peek: What’s in the Winter Issue of Ms.? Groundbreaking Reporting on Women’s Health and Power

PUBLISHED 12/26/2025 by

Mifepristone has shown potential to treat a striking range of diseases and conditions, some life-threatening: fibroids, breast cancer, depression, endometriosis, Gulf War illness and maybe even other autoimmune diseases, such as chronic fatigue syndrome and multiple sclerosis. Research also suggests that mifepristone may help prevent some forms of breast cancer and can serve as an effective weekly contraceptive without the side effects of hormonal birth control.

Yet despite the drug’s promise, its development has been repeatedly stymied by abortion opponents who fear wider availability would weaken their attempts to suppress abortion access. 

The result? Women are left in needless pain and subject to invasive and unnecessary surgical procedures like hysterectomies.

A Century After the Eugenics Movement, the U.S. Is Again Barring Disabled Immigrants

PUBLISHED 11/20/2025 by

This month, Secretary of State Marco Rubio instructed visa officers to consider obesity and other chronic health conditions, such as heart disease, cancer and diabetes, as justification to deny people visas to the United States.

Many were outraged and shocked, observing the Trump administration’s new expansion of the “public charge” rule—directing visa officers to deny entry to people with disabilities, chronic illnesses or age-related conditions—as a modern revival of eugenic immigration policy designed to exclude, control and institutionalize disabled and marginalized people.

When Trump first took office in 2016, the Trump administration broadened the definition of public charge to include people who receive SNAP benefits, medicaid, housing assistance, childcare subsidies and more. This new rule was published in 2019 and went into effect in 2020 and early 2021; President Biden ended the use of this public charge rule definition in March 2021, returning it to the older but still restrictive version. Following Trump’s new rule, visa denials based on the “public charge” rule exploded during Trump’s first residency, rising from just over 1,000 denials in 2016 to over 20,000 in 2019, and it had disastrous effects.

As the Migration Policy Institute (MPI) found, broadening this public charge rule led many people to reduce or stop using benefits or services for themselves.

The War on Children

PUBLISHED 9/5/2025 by

American children die at stunning rates because of policy choices, and mostly because of policy choices made by the “pro-life” right.

The Republican Party has long claimed the mantle of defending life. The new Republican Party has promised to make America healthy again. Instead, they’re leaving kids sick and dead.

This is a war on children. It is also a war on women. The “women and children” framing can feel incredibly condescending, but the truth is that women’s and children’s lives and wellbeing are indelibly intertwined. Women make children with our bodies; if we are not well, they are not well. Women still do most of the work of raising and nurturing children; if they are not well, we are not well. This does not apply to every single woman on earth. But it applies to women as a class, and to children as a class.

One Mom, Two Kids and a Chronically Ill Husband: The Hidden Burden of Multigenerational Caregivers

PUBLISHED 4/11/2025 by

Lizzie, a 34-year-old mom who cares for her husband with long COVID, is emblematic of how the classic sandwich generation has evolved for our generation into the multigenerational caregiver—caring for multiple family members of, you guessed it, different generations; in Lizzie’s case, her husband and children. Since COVID, in particular, the age of multigenerational caregivers has become younger as more of us take on care of an affected spouse (or sibling).

‘The Future Is Disabled’: Leah Lakshmi Piepzna-Samarasinha on Creating a More Humane Social Order

PUBLISHED 10/5/2022 by

Writer, disability-justice activist and performance artist Leah Lakshmi Piepzna-Samarasinha knows that it’s possible for society to become more equitable. Piepzna-Samarasinha’s latest book, The Future Is Disabled: Prophesies, Love Notes and Mourning Songs, lays out a bare-bones agenda for what is needed to make the U.S. more socially just.

Piepzna-Samarasinha and Ms. contributor Eleanor J. Bader communicated about the book, the disability justice movement and the ways that activists can support each other in the fight for a more ecologically sustainable and humane social order.      

‘Vagina Obscura’ Author Rachel E. Gross Takes Us on a Daring Anatomical Voyage

PUBLISHED 4/26/2022 by

Rachel E. Gross, in her debut book Vagina Obscura: An Anatomical Voyage, takes us on a journey around “the organs traditionally bound up in baby-making―the uterus, ovaries and vagina,” elaborating both on what science knows, and what it doesn’t. (Did you know it wasn’t until 1993 that a federal mandate required researchers to include women and minorities in clinical research?)

Gross recently spoke to Carli Cutchin by phone from her home in Brooklyn. Thoughtful and erudite, she talked about the female and LGBT researchers who’ve made scientific inroads against the odds, the myth that the “clitoral” and “vaginal” orgasms are distinct from each other, a princess who relocated her clitoris, koala vaginas and much more.

To Lose My Chronic Pain, I Had to Find My Rage

PUBLISHED 2/12/2022 by

A personal story on chronic pain and repressed emotions—and why this disproportionally affects women:

“When our culture hits the ‘mute’ button on women’s anger, it isn’t just silencing us; it is also torturing us, disabling us and killing us.”

“The Lady’s Handbook for Her Mysterious Illness” Gives Voice to Women Suffering Chronic Pain

PUBLISHED 4/11/2020 by
THE LADY'S HANDBOOK FOR HER MYSTERIOUS ILLNESS

Twenty percent of the adult population in the U.S. suffer from chronic pain, and this pain typically will affect women more than men. My pursuit of a diagnosis and cure for my own illness became “The Lady’s Handbook for Her Mysterious Illness,” a memoir with a mission: to help the millions of women who suffer from unnamed or misunderstood conditions.